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Nervous tissue first arose in wormlike organisms about 550 to 600 million years ago.
In vertebrate species it consists of two main parts, the central nervous system (CNS) and the peripheral nervous system (PNS). The PNS consists mainly of nerves, which are enclosed bundles of the long fibers or axons, that connect the CNS to every other part of the body.
Nerves that exit from the cranium are called cranial nerves while those exiting from the spinal cord are called spinal nerves.
The nervous system derives its name from nerves, which are cylindrical bundles of fibers (the axons of neurons), that emanate from the brain and spinal cord, and branch repeatedly to innervate every part of the body.
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Recent findings indicate that glial cells, such as microglia and astrocytes, serve as important resident immune cells within the central nervous system.
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The vertebrate nervous system can also be divided into areas called grey matter ("gray matter" in American spelling) and white matter.
Grey matter (which is only grey in preserved tissue, and is better described as pink or light brown in living tissue) contains a high proportion of cell bodies of neurons.